3D cell culture refers to an artificially created environment that allows the growth of cells and the interaction of these with the surroundings covering all the three dimensions. The growing popularity of 3D cell culture can be attributed to its ability to overcome the problems pertaining to cellular behavior and characteristics posed by 2D cell culture. 3D cell culture promotes greater understanding of disease models via cellular modelling of various disease states.
The ability to replace animals in pharmaceutical testing and research, high demand for organ transplantation, rising investments, and greater research related activities are the key factors that drive the global 3D cell cultures market. Expanding at a remarkable CAGR of 29.1% from 2014 to 2020, the global 3D cell cultures market is projected to reach US$2717.6 million by the end of the forecast period from US$586.1 million in 2014.
Development of Spheroids: An Ongoing Trend in the Global 3D Cell Cultures Market
The global 3D cell cultures market is segmented on the basis of technology, application, end users, and geography. On the basis of technology, this market is categorized into microchips, scaffold-free platforms, gels, bioreactors, and extracellular matrices or scaffolds. The segment for extracellular matrices or scaffolds holds the highest share in the global 3D cell cultures market.
Application-wise, the global 3D cell cultures market is segmented into stem cell biology, clinical application, tissue engineering, drug development and testing, and research. The various end users in the global 3D cell cultures market are hospitals and diagnostic centers, biotechnology and pharmaceutical industries, research laboratories and institutes, and others. Pharmaceutical and biotechnology industries are by far the largest users of the 3D cell culture technology.
The field of 3D cell culture is open to improvements, and most users of 3D cell culture are mainly interested in developing spheroids. In fact presently, the global 3D cell cultures market is characterized by the adoption of technologies that support spheroid development. The application of 3D cell culture is seen extensively in the area of organ transplantation which calls for creating cultures from the cells of organs, bone marrow, and even the skin.
Europe: Dominant Regional Player
Geographically, the global 3D cell cultures market is segmented into Asia, North America, Europe, and Rest of the World. Europe holds the largest share in the global 3D cell cultures market with the U.K. representing the largest market for 3D cell cultures. The U.K. market for 3D cell cultures is mainly propelled by extensive R&D in the field of 3D cell cultures and high investments.
Developing at a robust CAGR of 28.7% from 2014 to 2020, the 3D cell cultures market in Europe is anticipated to reach US$1067.8 million by 2020 from US$234.4 million in 2014. Presently, the global 3D cell cultures market is characterized by the use of laboratory automation for 3D cell culturing. Lack of consistency in the products and budgetary constraints are factors that hamper the growth of the global 3D cell cultures market. However, shift of focus towards regenerative medicine and the use of microfluidic technology will create several opportunities for further expansion of the global 3D cell cultures market.
The prominent companies in the global 3D cell cultures market are 3D Biomatrix Inc., Lonza Group, 3D Biotek LLC, Becton, Dickinson & Company, Corning Incorporated, Thermo Fisher Scientific Inc., and Sigma-Aldrich Corporation.